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Characterization of the 8-hydroxyquinoline scaffold for inhibitors of West Nile virus serine protease

West Nile virus (WNV) is a mosquito-borne member of flaviviruses that causes significant morbidity and mortality especially among children. There is currently no approved vaccine or antiviral therapeutic for human use. In a previous study, we described compounds containing the 8-hydroxyquinoline (8-...

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Bibliographic Details
Main Authors: Ezgimen, Manolya, Lai, Huiguo, Mueller, Niklaus H., Lee, Kyungae, Cuny, Gregory, Ostrov, David A., Padmanabhan, Radhakrishnan
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331929/
https://ncbi.nlm.nih.gov/pubmed/22343093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2012.02.003
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