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Effects of Detergents on the West Nile virus Protease Activity

Detergents such as Triton X-100 are often used in drug discovery research to weed out small molecule promiscuous and non-specific inhibitors which act by aggregation in solution and undesirable precipitation in aqueous assay buffers. We evaluated the effects of commonly used detergents, Triton X-100...

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Detalhes bibliográficos
Main Authors: Ezgimen, Manolya D., Mueller, Niklaus H., Teramoto, Tadahisa, Padmanabhan, R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817951/
https://ncbi.nlm.nih.gov/pubmed/19369080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.03.050
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