In vitro biosynthesis of a universal t(6)A tRNA modification in Archaea and Eukarya

N(6)-threonylcarbamoyladenosine (t(6)A) is a modified nucleotide found in all transfer RNAs (tRNAs) decoding codons starting with adenosine. Its role is to facilitate codon–anticodon pairing and to prevent frameshifting during protein synthesis. Genetic studies demonstrated that two universal protei...

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Autors principals: Perrochia, Ludovic, Crozat, Estelle, Hecker, Arnaud, Zhang, Wenhua, Bareille, Joseph, Collinet, Bruno, van Tilbeurgh, Herman, Forterre, Patrick, Basta, Tamara
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
Matèries:
RNA
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561968/
https://ncbi.nlm.nih.gov/pubmed/23258706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1287
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