In vitro biosynthesis of a universal t(6)A tRNA modification in Archaea and Eukarya

N(6)-threonylcarbamoyladenosine (t(6)A) is a modified nucleotide found in all transfer RNAs (tRNAs) decoding codons starting with adenosine. Its role is to facilitate codon–anticodon pairing and to prevent frameshifting during protein synthesis. Genetic studies demonstrated that two universal protei...

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Main Authors: Perrochia, Ludovic, Crozat, Estelle, Hecker, Arnaud, Zhang, Wenhua, Bareille, Joseph, Collinet, Bruno, van Tilbeurgh, Herman, Forterre, Patrick, Basta, Tamara
格式: Artigo
語言:Inglês
出版: Oxford University Press 2013
主題:
RNA
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561968/
https://ncbi.nlm.nih.gov/pubmed/23258706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1287
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