Structure–function analysis of Sua5 protein reveals novel functional motifs required for the biosynthesis of the universal t(6)A tRNA modification

N(6)-threonyl-carbamoyl adenosine (t(6)A) is a universal tRNA modification found at position 37, next to the anticodon, in almost all tRNAs decoding ANN codons (where N = A, U, G, or C). t(6)A stabilizes the codon–anticodon interaction and hence promotes translation fidelity. The first step of the b...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:RNA
Autori principali: Pichard-Kostuch, Adeline, Zhang, Wenhua, Liger, Dominique, Daugeron, Marie-Claire, Létoquart, Juliette, Li de la Sierra-Gallay, Ines, Forterre, Patrick, Collinet, Bruno, van Tilbeurgh, Herman, Basta, Tamara
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004061/
https://ncbi.nlm.nih.gov/pubmed/29650678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.066092.118
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi