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In vitro biosynthesis of a universal t(6)A tRNA modification in Archaea and Eukarya
N(6)-threonylcarbamoyladenosine (t(6)A) is a modified nucleotide found in all transfer RNAs (tRNAs) decoding codons starting with adenosine. Its role is to facilitate codon–anticodon pairing and to prevent frameshifting during protein synthesis. Genetic studies demonstrated that two universal protei...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3561968/ https://ncbi.nlm.nih.gov/pubmed/23258706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1287 |
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