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In vitro biosynthesis of a universal t(6)A tRNA modification in Archaea and Eukarya
N(6)-threonylcarbamoyladenosine (t(6)A) is a modified nucleotide found in all transfer RNAs (tRNAs) decoding codons starting with adenosine. Its role is to facilitate codon–anticodon pairing and to prevent frameshifting during protein synthesis. Genetic studies demonstrated that two universal protei...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3561968/ https://ncbi.nlm.nih.gov/pubmed/23258706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1287 |
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