Cross Kingdom Functional Conservation of the Core Universally Conserved Threonylcarbamoyladenosine tRNA Synthesis Enzymes

Threonylcarbamoyladenosine (t(6)A) is a universal modification located in the anticodon stem-loop of tRNAs. In yeast, both cytoplasmic and mitochondrial tRNAs are modified. The cytoplasmic t(6)A synthesis pathway was elucidated and requires Sua5p, Kae1p, and four other KEOPS complex proteins. Recent...

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Autori principali: Thiaville, Patrick C., El Yacoubi, Basma, Perrochia, Ludovic, Hecker, Arnaud, Prigent, Magali, Thiaville, Jennifer J., Forterre, Patrick, Namy, Olivier, Basta, Tamara, de Crécy-Lagard, Valérie
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187629/
https://ncbi.nlm.nih.gov/pubmed/25038083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00147-14
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