Essentiality of threonylcarbamoyladenosine (t(6)A), a universal tRNA modification, in bacteria

Threonylcarbamoyladenosine (t(6)A) is a modified nucleoside universally conserved in tRNAs in all three kingdoms of life. The recently discovered genes for t(6)A synthesis, including tsaC and tsaD, are essential in model prokaryotes but not essential in yeast. These genes had been identified as anti...

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Detalhes bibliográficos
Publicado no:Mol Microbiol
Main Authors: Thiaville, Patrick C., Yacoubi, Basma El, Köhrer, Caroline, Thiaville, Jennifer J., Deutsch, Chris, Iwata-Reuyl, Dirk, Bacusmo, Jo Marie, Armengaud, Jean, Bessho, Yoshitaka, Wetzel, Collin, Cao, Xiaoyu, Limbach, Patrick A., RajBhandary, Uttam L., de Crécy-Lagard, Valérie
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963248/
https://ncbi.nlm.nih.gov/pubmed/26337258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13209
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