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Biosynthesis of Threonylcarbamoyl Adenosine (t(6)A), a Universal tRNA Nucleoside

The anticodon stem-loop (ASL) of transfer RNAs (tRNAs) drives decoding by interacting directly with the mRNA through codon/anticodon pairing. Chemically complex nucleoside modifications found in the ASL at positions 34 or 37 are known to be required for accurate decoding. Although over 100 distinct...

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Detalhes bibliográficos
Main Authors: Deutsch, Christopher, El Yacoubi, Basma, de Crécy-Lagard, Valérie, Iwata-Reuyl, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340167/
https://ncbi.nlm.nih.gov/pubmed/22378793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.344028
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