Specificity in the biosynthesis of the universal tRNA nucleoside N(6)-threonylcarbamoyl adenosine (t(6)A)—TsaD is the gatekeeper

N(6)-threonylcarbamoyl adenosine (t(6)A) is a nucleoside modification found in all kingdoms of life at position 37 of tRNAs decoding ANN codons, which functions in part to restrict translation initiation to AUG and suppress frameshifting at tandem ANN codons. In Bacteria the proteins TsaB, TsaC (or...

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Publicado no:RNA
Main Authors: Swinehart, William, Deutsch, Christopher, Sarachan, Kathryn L., Luthra, Amit, Bacusmo, Jo Marie, de Crécy-Lagard, Valérie, Swairjo, Manal A., Agris, Paul F., Iwata-Reuyl, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430679/
https://ncbi.nlm.nih.gov/pubmed/32385138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.075747.120
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