Specificity in the biosynthesis of the universal tRNA nucleoside N(6)-threonylcarbamoyl adenosine (t(6)A)—TsaD is the gatekeeper

N(6)-threonylcarbamoyl adenosine (t(6)A) is a nucleoside modification found in all kingdoms of life at position 37 of tRNAs decoding ANN codons, which functions in part to restrict translation initiation to AUG and suppress frameshifting at tandem ANN codons. In Bacteria the proteins TsaB, TsaC (or...

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Udgivet i:RNA
Main Authors: Swinehart, William, Deutsch, Christopher, Sarachan, Kathryn L., Luthra, Amit, Bacusmo, Jo Marie, de Crécy-Lagard, Valérie, Swairjo, Manal A., Agris, Paul F., Iwata-Reuyl, Dirk
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430679/
https://ncbi.nlm.nih.gov/pubmed/32385138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.075747.120
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