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NMR-based Structural Analysis of Threonylcarbamoyl-AMP Synthase and Its Substrate Interactions

The hypermodified nucleoside N(6)-threonylcarbamoyladenosine (t(6)A(37)) is present in many distinct tRNA species and has been found in organisms in all domains of life. This post-transcriptional modification enhances translation fidelity by stabilizing the anticodon/codon interaction in the ribosom...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Harris, Kimberly A., Bobay, Benjamin G., Sarachan, Kathryn L., Sims, Alexis F., Bilbille, Yann, Deutsch, Christopher, Iwata-Reuyl, Dirk, Agris, Paul F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536411/
https://ncbi.nlm.nih.gov/pubmed/26060251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.631242
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