Essentiality of threonylcarbamoyladenosine (t(6)A), a universal tRNA modification, in bacteria

Threonylcarbamoyladenosine (t(6)A) is a modified nucleoside universally conserved in tRNAs in all three kingdoms of life. The recently discovered genes for t(6)A synthesis, including tsaC and tsaD, are essential in model prokaryotes but not essential in yeast. These genes had been identified as anti...

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Publié dans:Mol Microbiol
Auteurs principaux: Thiaville, Patrick C., Yacoubi, Basma El, Köhrer, Caroline, Thiaville, Jennifer J., Deutsch, Chris, Iwata-Reuyl, Dirk, Bacusmo, Jo Marie, Armengaud, Jean, Bessho, Yoshitaka, Wetzel, Collin, Cao, Xiaoyu, Limbach, Patrick A., RajBhandary, Uttam L., de Crécy-Lagard, Valérie
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963248/
https://ncbi.nlm.nih.gov/pubmed/26337258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13209
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