In vitro biosynthesis of a universal t(6)A tRNA modification in Archaea and Eukarya

N(6)-threonylcarbamoyladenosine (t(6)A) is a modified nucleotide found in all transfer RNAs (tRNAs) decoding codons starting with adenosine. Its role is to facilitate codon–anticodon pairing and to prevent frameshifting during protein synthesis. Genetic studies demonstrated that two universal protei...

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Autores principales: Perrochia, Ludovic, Crozat, Estelle, Hecker, Arnaud, Zhang, Wenhua, Bareille, Joseph, Collinet, Bruno, van Tilbeurgh, Herman, Forterre, Patrick, Basta, Tamara
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561968/
https://ncbi.nlm.nih.gov/pubmed/23258706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1287
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