In vitro biosynthesis of a universal t(6)A tRNA modification in Archaea and Eukarya

N(6)-threonylcarbamoyladenosine (t(6)A) is a modified nucleotide found in all transfer RNAs (tRNAs) decoding codons starting with adenosine. Its role is to facilitate codon–anticodon pairing and to prevent frameshifting during protein synthesis. Genetic studies demonstrated that two universal protei...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Perrochia, Ludovic, Crozat, Estelle, Hecker, Arnaud, Zhang, Wenhua, Bareille, Joseph, Collinet, Bruno, van Tilbeurgh, Herman, Forterre, Patrick, Basta, Tamara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561968/
https://ncbi.nlm.nih.gov/pubmed/23258706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1287
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