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Triggering of Inflammasome by Aggregated α–Synuclein, an Inflammatory Response in Synucleinopathies

Parkinson’s disease (PD) is one of the most common neurodegenerative diseases. It is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta of the brain. Another feature is represented by the formation in these cells of inclusions called Lewy bodies (LB), principally...

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Detalhes bibliográficos
Main Authors: Codolo, Gaia, Plotegher, Nicoletta, Pozzobon, Tommaso, Brucale, Marco, Tessari, Isabella, Bubacco, Luigi, de Bernard, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561263/
https://ncbi.nlm.nih.gov/pubmed/23383169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055375
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