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NADH fluorescence lifetime is an endogenous reporter of α-synuclein aggregation in live cells
α-Synuclein (aS) aggregation has been amply investigated for its involvement in Parkinson’s disease because its amyloid fibrils are the main constituent of Lewy bodies, one of the hallmarks of the disease. aS aggregation was studied here in vitro and in cellular models to correlate aggregation produ...
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| 發表在: | FASEB J |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Federation of American Societies for Experimental
Biology
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4447231/ https://ncbi.nlm.nih.gov/pubmed/25713058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-260281 |
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