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NADH fluorescence lifetime is an endogenous reporter of α-synuclein aggregation in live cells

α-Synuclein (aS) aggregation has been amply investigated for its involvement in Parkinson’s disease because its amyloid fibrils are the main constituent of Lewy bodies, one of the hallmarks of the disease. aS aggregation was studied here in vitro and in cellular models to correlate aggregation produ...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Plotegher, Nicoletta, Stringari, Chiara, Jahid, Sohail, Veronesi, Marina, Girotto, Stefania, Gratton, Enrico, Bubacco, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447231/
https://ncbi.nlm.nih.gov/pubmed/25713058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-260281
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