NADH fluorescence lifetime is an endogenous reporter of α-synuclein aggregation in live cells

α-Synuclein (aS) aggregation has been amply investigated for its involvement in Parkinson’s disease because its amyloid fibrils are the main constituent of Lewy bodies, one of the hallmarks of the disease. aS aggregation was studied here in vitro and in cellular models to correlate aggregation produ...

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Bibliographic Details
Published in:FASEB J
Main Authors: Plotegher, Nicoletta, Stringari, Chiara, Jahid, Sohail, Veronesi, Marina, Girotto, Stefania, Gratton, Enrico, Bubacco, Luigi
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2015
Subjects:
Research Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447231/
https://ncbi.nlm.nih.gov/pubmed/25713058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-260281
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