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NADH fluorescence lifetime is an endogenous reporter of α-synuclein aggregation in live cells

α-Synuclein (aS) aggregation has been amply investigated for its involvement in Parkinson’s disease because its amyloid fibrils are the main constituent of Lewy bodies, one of the hallmarks of the disease. aS aggregation was studied here in vitro and in cellular models to correlate aggregation produ...

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Dettagli Bibliografici
Pubblicato in:FASEB J
Autori principali: Plotegher, Nicoletta, Stringari, Chiara, Jahid, Sohail, Veronesi, Marina, Girotto, Stefania, Gratton, Enrico, Bubacco, Luigi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447231/
https://ncbi.nlm.nih.gov/pubmed/25713058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-260281
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