Triggering of Inflammasome by Aggregated α–Synuclein, an Inflammatory Response in Synucleinopathies

Parkinson’s disease (PD) is one of the most common neurodegenerative diseases. It is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta of the brain. Another feature is represented by the formation in these cells of inclusions called Lewy bodies (LB), principally...

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Bibliographic Details
Main Authors: Codolo, Gaia, Plotegher, Nicoletta, Pozzobon, Tommaso, Brucale, Marco, Tessari, Isabella, Bubacco, Luigi, de Bernard, Marina
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561263/
https://ncbi.nlm.nih.gov/pubmed/23383169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055375
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