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Triggering of Inflammasome by Aggregated α–Synuclein, an Inflammatory Response in Synucleinopathies

Parkinson’s disease (PD) is one of the most common neurodegenerative diseases. It is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta of the brain. Another feature is represented by the formation in these cells of inclusions called Lewy bodies (LB), principally...

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Détails bibliographiques
Auteurs principaux: Codolo, Gaia, Plotegher, Nicoletta, Pozzobon, Tommaso, Brucale, Marco, Tessari, Isabella, Bubacco, Luigi, de Bernard, Marina
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561263/
https://ncbi.nlm.nih.gov/pubmed/23383169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055375
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