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Conformational Equilibria in Monomeric α-Synuclein at the Single-Molecule Level
Human α-Synuclein (αSyn) is a natively unfolded protein whose aggregation into amyloid fibrils is involved in the pathology of Parkinson disease. A full comprehension of the structure and dynamics of early intermediates leading to the aggregated states is an unsolved problem of essential importance...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2174973/ https://ncbi.nlm.nih.gov/pubmed/18198943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0060006 |
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