Conformational Equilibria in Monomeric α-Synuclein at the Single-Molecule Level

Human α-Synuclein (αSyn) is a natively unfolded protein whose aggregation into amyloid fibrils is involved in the pathology of Parkinson disease. A full comprehension of the structure and dynamics of early intermediates leading to the aggregated states is an unsolved problem of essential importance...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Sandal, Massimo, Valle, Francesco, Tessari, Isabella, Mammi, Stefano, Bergantino, Elisabetta, Musiani, Francesco, Brucale, Marco, Bubacco, Luigi, Samorì, Bruno
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2008
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174973/
https://ncbi.nlm.nih.gov/pubmed/18198943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0060006
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