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Worm-Like Ising Model for Protein Mechanical Unfolding under the Effect of Osmolytes
We show via single-molecule mechanical unfolding experiments that the osmolyte glycerol stabilizes the native state of the human cardiac I27 titin module against unfolding without shifting its unfolding transition state on the mechanical reaction coordinate. Taken together with similar findings on t...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3260691/ https://ncbi.nlm.nih.gov/pubmed/22339871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.12.007 |
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