High-Pressure-Driven Reversible Dissociation of α-Synuclein Fibrils Reveals Structural Hierarchy

The analysis of the α-synuclein (aS) aggregation process, which is involved in Parkinson’s disease etiopathogenesis, and of the structural feature of the resulting amyloid fibrils may shed light on the relationship between the structure of aS aggregates and their toxicity. This may be considered a p...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biophys J
Egile Nagusiak: Piccirilli, Federica, Plotegher, Nicoletta, Ortore, Maria Grazia, Tessari, Isabella, Brucale, Marco, Spinozzi, Francesco, Beltramini, Mariano, Mariani, Paolo, Militello, Valeria, Lupi, Stefano, Perucchi, Andrea, Bubacco, Luigi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2017
Gaiak:
Proteins
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647593/
https://ncbi.nlm.nih.gov/pubmed/29045863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.08.042
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