Covalent α-Synuclein Dimers: Chemico-Physical and Aggregation Properties

The aggregation of α-synuclein into amyloid fibrils constitutes a key step in the onset of Parkinson's disease. Amyloid fibrils of α-synuclein are the major component of Lewy bodies, histological hallmarks of the disease. Little is known about the mechanism of aggregation of α-synuclein. During...

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Main Authors: Pivato, Micaela, De Franceschi, Giorgia, Tosatto, Laura, Frare, Erica, Kumar, Dhruv, Aioanei, Daniel, Brucale, Marco, Tessari, Isabella, Bisaglia, Marco, Samori, Bruno, de Laureto, Patrizia Polverino, Bubacco, Luigi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521728/
https://ncbi.nlm.nih.gov/pubmed/23272053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050027
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