Structural and Morphological Characterization of Aggregated Species of α-Synuclein Induced by Docosahexaenoic Acid

The interaction of brain lipids with α-synuclein may play an important role in the pathogenesis of Parkinson disease (PD). Docosahexaenoic acid (DHA) is an abundant fatty acid of neuronal membranes, and it is presents at high levels in brain areas with α-synuclein inclusions of patients with PD. In...

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Detalhes bibliográficos
Main Authors: De Franceschi, Giorgia, Frare, Erica, Pivato, Micaela, Relini, Annalisa, Penco, Amanda, Greggio, Elisa, Bubacco, Luigi, Fontana, Angelo, de Laureto, Patrizia Polverino
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121372/
https://ncbi.nlm.nih.gov/pubmed/21527634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.202937
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