Structural and Morphological Characterization of Aggregated Species of α-Synuclein Induced by Docosahexaenoic Acid

The interaction of brain lipids with α-synuclein may play an important role in the pathogenesis of Parkinson disease (PD). Docosahexaenoic acid (DHA) is an abundant fatty acid of neuronal membranes, and it is presents at high levels in brain areas with α-synuclein inclusions of patients with PD. In...

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Main Authors: De Franceschi, Giorgia, Frare, Erica, Pivato, Micaela, Relini, Annalisa, Penco, Amanda, Greggio, Elisa, Bubacco, Luigi, Fontana, Angelo, de Laureto, Patrizia Polverino
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2011
Ábhair:
Protein Structure and Folding
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121372/
https://ncbi.nlm.nih.gov/pubmed/21527634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.202937
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