Structural and Morphological Characterization of Aggregated Species of α-Synuclein Induced by Docosahexaenoic Acid

The interaction of brain lipids with α-synuclein may play an important role in the pathogenesis of Parkinson disease (PD). Docosahexaenoic acid (DHA) is an abundant fatty acid of neuronal membranes, and it is presents at high levels in brain areas with α-synuclein inclusions of patients with PD. In...

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Hlavní autoři: De Franceschi, Giorgia, Frare, Erica, Pivato, Micaela, Relini, Annalisa, Penco, Amanda, Greggio, Elisa, Bubacco, Luigi, Fontana, Angelo, de Laureto, Patrizia Polverino
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121372/
https://ncbi.nlm.nih.gov/pubmed/21527634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.202937
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