Xylosyl- and glucuronyltransferase functions of LARGE in α-dystroglycan modification are conserved in LARGE2

LARGE-dependent modification enables α-dystroglycan (α-DG) to bind to its extracellular matrix ligands. Mutations in the LARGE gene and several others involved in O-mannosyl glycan synthesis have been identified in congenital and limb-girdle muscular dystrophies that are characterized by perturbed g...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Inamori, Kei-ichiro, Hara, Yuji, Willer, Tobias, Anderson, Mary E, Zhu, Zihan, Yoshida-Moriguchi, Takako, Campbell, Kevin P
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555503/
https://ncbi.nlm.nih.gov/pubmed/23125099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cws152
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