Like-acetylglucosaminyltransferase (LARGE)-dependent modification of dystroglycan at Thr-317/319 is required for laminin binding and arenavirus infection

α-dystroglycan is a highly O-glycosylated extracellular matrix receptor that is required for anchoring of the basement membrane to the cell surface and for the entry of Old World arenaviruses into cells. Like-acetylglucosaminyltransferase (LARGE) is a key molecule that binds to the N-terminal domain...

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Bibliographic Details
Main Authors: Hara, Yuji, Kanagawa, Motoi, Kunz, Stefan, Yoshida-Moriguchi, Takako, Satz, Jakob S., Kobayashi, Yvonne M., Zhu, Zihan, Burden, Steven J., Oldstone, Michael B. A., Campbell, Kevin P.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198351/
https://ncbi.nlm.nih.gov/pubmed/21987822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114836108
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