Posttranslational Modification of α-Dystroglycan, the Cellular Receptor for Arenaviruses, by the Glycosyltransferase LARGE Is Critical for Virus Binding

The receptor for lymphocytic choriomeningitis virus (LCMV), the human pathogenic Lassa fever virus (LFV), and clade C New World arenaviruses is α-dystroglycan (α-DG), a cell surface receptor for proteins of the extracellular matrix (ECM). Specific posttranslational modification of α-DG by the glycos...

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Autores principales: Kunz, Stefan, Rojek, Jillian M., Kanagawa, Motoi, Spiropoulou, Christina F., Barresi, Rita, Campbell, Kevin P., Oldstone, Michael B. A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280193/
https://ncbi.nlm.nih.gov/pubmed/16254363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.14282-14296.2005
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