Loss of α-Dystroglycan Laminin Binding in Epithelium-derived Cancers Is Caused by Silencing of LARGE

The interaction between epithelial cells and the extracellular matrix is crucial for tissue architecture and function and is compromised during cancer progression. Dystroglycan is a membrane receptor that mediates interactions between cells and basement membranes in various epithelia. In many epithe...

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Detalhes bibliográficos
Main Authors: de Bernabé, Daniel Beltrán-Valero, Inamori, Kei-ichiro, Yoshida-Moriguchi, Takako, Weydert, Christine J., Harper, Hollie A., Willer, Tobias, Henry, Michael D., Campbell, Kevin P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670132/
https://ncbi.nlm.nih.gov/pubmed/19244252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C900007200
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