Loss of α-Dystroglycan Laminin Binding in Epithelium-derived Cancers Is Caused by Silencing of LARGE

The interaction between epithelial cells and the extracellular matrix is crucial for tissue architecture and function and is compromised during cancer progression. Dystroglycan is a membrane receptor that mediates interactions between cells and basement membranes in various epithelia. In many epithe...

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Autori principali: de Bernabé, Daniel Beltrán-Valero, Inamori, Kei-ichiro, Yoshida-Moriguchi, Takako, Weydert, Christine J., Harper, Hollie A., Willer, Tobias, Henry, Michael D., Campbell, Kevin P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
Soggetti:
Glycobiology and Extracellular Matrices
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670132/
https://ncbi.nlm.nih.gov/pubmed/19244252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C900007200
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