Indoleamine 2,3-dioxygenase inhibition attenuates lipopolysaccharide induced persistent microglial activation and depressive-like complications in fractalkine receptor (CX(3)CR1)-deficient mice

An impaired ability to regulate the activation of microglia by fractalkine (CX(3)CL1) leads to persistent neuroinflammation and behavioral alterations following lipopolysaccharide (LPS) challenge. While these responses are usually transient, LPS injection caused prolonged depressive-like behavior in...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Corona, Angela W., Norden, Diana M., Skendelas, John P., Huang, Yan, O’Connor, Jason C., Lawson, Marcus, Dantzer, Robert, Kelley, Keith W., Godbout, Jonathan P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554840/
https://ncbi.nlm.nih.gov/pubmed/22926082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2012.08.008
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge