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Spatio-temporal differences in the profile of murine brain expression of proinflammatory cytokines and indoleamine 2,3-dioxygenase in response to peripheral lipopolysaccharide administration

The mechanisms underlying in vivo activation of indoleamine 2,3-dioxygenase (IDO), a tryptophan-catabolizing enzyme that mediates in the brain, the induction of depressive-like behavior by peripheral innate immune system stimulation are still poorly understood. By monitoring how cytokines parallel I...

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Bibliografiske detaljer
Main Authors: André, Caroline, O'Connor, Jason C., Kelley, Keith W., Lestage, Jacques, Dantzer, Robert, Castanon, Nathalie
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2571040/
https://ncbi.nlm.nih.gov/pubmed/18653240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2008.06.011
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