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The role of indoleamine 2,3-dioxygenase in LP-BPM5 murine retroviral disease progression

BACKGROUND: Indoleamine 2,3-dioxygenase (IDO) is an immunomodulatory intracellular enzyme involved in tryptophan degradation. IDO is induced during cancer and microbial infections by cytokines, ligation of co-stimulatory molecules and/or activation of pattern recognition receptors, ultimately leadin...

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Detalhes bibliográficos
Main Authors: O’Connor, Megan A, Green, William R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751850/
https://ncbi.nlm.nih.gov/pubmed/23680027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-154
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