Interferon-γ and Tumor Necrosis Factor-α Mediate the Upregulation of Indoleamine 2,3-Dioxygenase and the Induction of Depressive-Like Behavior in Mice in Response to Bacillus Calmette-Guérin

Although the tryptophan-degrading enzyme, indoleamine 2,3-dioxygenase (IDO), is a pivotal mediator of inflammation-induced depression, its mechanism of regulation has not yet been investigated in this context. Here, we demonstrate an essential role for interferon (IFN)γ and tumor necrosis factor (TN...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: O'Connor, Jason C., André, Caroline, Wang, Yunxia, Lawson, Marcus A., Szegedi, Sandra S., Lestage, Jacques, Castanon, Nathalie, Kelley, Keith W., Dantzer, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835569/
https://ncbi.nlm.nih.gov/pubmed/19339614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5032-08.2009
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados