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LPS-induced indoleamine 2,3-dioxygenase is regulated in an interferon-c- 3 independent manner by a JNK signaling pathway in primary murine microglia
Inflammation-induced activation of the tryptophan catabolizing enzyme indoleamine 2,3-dioxygenase (IDO) causes depressive-like behavior in mice following acute activation of the innate immune system by lipopolysaccharide (LPS). Here we investigated the mechanism of IDO expression induced by LPS in p...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818058/ https://ncbi.nlm.nih.gov/pubmed/19577630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2009.06.152 |
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