Fractalkine receptor (CX(3)CR1) deficiency sensitizes mice to the behavioral changes induced by lipopolysaccharide

BACKGROUND: Interactions between fractalkine (CX(3)CL1) and fractalkine receptor (CX(3)CR1) regulate microglial activation in the CNS. Recent findings indicate that age-associated impairments in CX(3)CL1 and CX(3)CR1 are directly associated with exaggerated microglial activation and an impaired reco...

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Autori principali: Corona, Angela W, Huang, Yan, O'Connor, Jason C, Dantzer, Robert, Kelley, Keith W, Popovich, Phillip G, Godbout, Jonathan P
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018416/
https://ncbi.nlm.nih.gov/pubmed/21167054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-7-93
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