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The MYC-Associated Protein CDCA7 Is Phosphorylated by AKT To Regulate MYC-Dependent Apoptosis and Transformation

Cell division control protein A7 (CDCA7) is a recently identified target of MYC-dependent transcriptional regulation. We have discovered that CDCA7 associates with MYC and that this association is modulated in a phosphorylation-dependent manner. The prosurvival kinase AKT phosphorylates CDCA7 at thr...

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Bibliographic Details
Main Authors: Gill, R. Montgomery, Gabor, Timothy V., Couzens, Amber L., Scheid, Michael P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554214/
https://ncbi.nlm.nih.gov/pubmed/23166294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00276-12
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