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Identification of small molecules that induce apoptosis in a Myc-dependent manner and inhibit Myc-driven transformation
The Myc transcription factor plays a central role in the regulation of cell cycle progression, apoptosis, angiogenesis, and cellular transformation. Myc is a potent oncoprotein that is deregulated in a wide variety of human tumors and is therefore an attractive target for novel cancer therapies. Usi...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1435363/ https://ncbi.nlm.nih.gov/pubmed/16606833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601418103 |
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