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Transformation of mouse T cells requires MYC and AKT activity in conjunction with inhibition of intrinsic apoptosis
Peripheral T-cell lymphoma is an aggressive non-Hodgkin's lymphoma characterized by excessive proliferation of transformed mature T cells. The number and nature of genetic aberrations required and sufficient for transformation of normal T cells into lymphomas is unknown. Here, using a combinato...
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| Опубликовано в: : | Oncotarget |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Impact Journals LLC
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5940390/ https://ncbi.nlm.nih.gov/pubmed/29765548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25113 |
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