Akt Phosphorylates and Negatively Regulates Apoptosis Signal-Regulating Kinase 1

The Akt family of serine/threonine-directed kinases promotes cellular survival in part by phosphorylating and inhibiting death-inducing proteins. Here we describe a novel functional interaction between Akt and apoptosis signal-regulating kinase 1 (ASK1), a mitogen-activated protein kinase kinase kin...

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Detalhes bibliográficos
Main Authors: Kim, Albert H., Khursigara, Gus, Sun, Xuan, Franke, Thomas F., Chao, Moses V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86680/
https://ncbi.nlm.nih.gov/pubmed/11154276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.3.893-901.2001
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