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Rho GTPase/Rho Kinase Negatively Regulates Endothelial Nitric Oxide Synthase Phosphorylation through the Inhibition of Protein Kinase B/Akt in Human Endothelial Cells

Endothelial nitric oxide synthase (eNOS) is an important regulator of cardiovascular homeostasis by production of nitric oxide (NO) from vascular endothelial cells. It can be activated by protein kinase B (PKB)/Akt via phosphorylation at Ser-1177. We are interested in the role of Rho GTPase/Rho kina...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Ming, Xiu-Fen, Viswambharan, Hema, Barandier, Christine, Ruffieux, Jean, Kaibuchi, Kozo, Rusconi, Sandro, Yang, Zhihong
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2002
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On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139860/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12446767/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.24.8467-8477.2002
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