Rho GTPase/Rho Kinase Negatively Regulates Endothelial Nitric Oxide Synthase Phosphorylation through the Inhibition of Protein Kinase B/Akt in Human Endothelial Cells

Endothelial nitric oxide synthase (eNOS) is an important regulator of cardiovascular homeostasis by production of nitric oxide (NO) from vascular endothelial cells. It can be activated by protein kinase B (PKB)/Akt via phosphorylation at Ser-1177. We are interested in the role of Rho GTPase/Rho kina...

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Detalhes bibliográficos
Main Authors: Ming, Xiu-Fen, Viswambharan, Hema, Barandier, Christine, Ruffieux, Jean, Kaibuchi, Kozo, Rusconi, Sandro, Yang, Zhihong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC139860/
https://ncbi.nlm.nih.gov/pubmed/12446767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.24.8467-8477.2002
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