Rho GTPase/Rho Kinase Negatively Regulates Endothelial Nitric Oxide Synthase Phosphorylation through the Inhibition of Protein Kinase B/Akt in Human Endothelial Cells

Endothelial nitric oxide synthase (eNOS) is an important regulator of cardiovascular homeostasis by production of nitric oxide (NO) from vascular endothelial cells. It can be activated by protein kinase B (PKB)/Akt via phosphorylation at Ser-1177. We are interested in the role of Rho GTPase/Rho kina...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Ming, Xiu-Fen, Viswambharan, Hema, Barandier, Christine, Ruffieux, Jean, Kaibuchi, Kozo, Rusconi, Sandro, Yang, Zhihong
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2002
נושאים:
Cell Growth and Development
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC139860/
https://ncbi.nlm.nih.gov/pubmed/12446767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.24.8467-8477.2002
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