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Rho GTPase/Rho Kinase Negatively Regulates Endothelial Nitric Oxide Synthase Phosphorylation through the Inhibition of Protein Kinase B/Akt in Human Endothelial Cells

Endothelial nitric oxide synthase (eNOS) is an important regulator of cardiovascular homeostasis by production of nitric oxide (NO) from vascular endothelial cells. It can be activated by protein kinase B (PKB)/Akt via phosphorylation at Ser-1177. We are interested in the role of Rho GTPase/Rho kina...

詳細記述

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書誌詳細
出版年:Mol Cell Biol
主要な著者: Ming, Xiu-Fen, Viswambharan, Hema, Barandier, Christine, Ruffieux, Jean, Kaibuchi, Kozo, Rusconi, Sandro, Yang, Zhihong
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139860/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12446767/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.24.8467-8477.2002
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