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Rho GTPase/Rho Kinase Negatively Regulates Endothelial Nitric Oxide Synthase Phosphorylation through the Inhibition of Protein Kinase B/Akt in Human Endothelial Cells

Endothelial nitric oxide synthase (eNOS) is an important regulator of cardiovascular homeostasis by production of nitric oxide (NO) from vascular endothelial cells. It can be activated by protein kinase B (PKB)/Akt via phosphorylation at Ser-1177. We are interested in the role of Rho GTPase/Rho kina...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Ming, Xiu-Fen, Viswambharan, Hema, Barandier, Christine, Ruffieux, Jean, Kaibuchi, Kozo, Rusconi, Sandro, Yang, Zhihong
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2002
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139860/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12446767/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.24.8467-8477.2002
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