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Akt Phosphorylates and Negatively Regulates Apoptosis Signal-Regulating Kinase 1
The Akt family of serine/threonine-directed kinases promotes cellular survival in part by phosphorylating and inhibiting death-inducing proteins. Here we describe a novel functional interaction between Akt and apoptosis signal-regulating kinase 1 (ASK1), a mitogen-activated protein kinase kinase kin...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2001
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC86680/ https://ncbi.nlm.nih.gov/pubmed/11154276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.3.893-901.2001 |
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