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Allosteric mechanisms of G protein coupled receptor signaling: a structural perspective
G protein-Coupled Receptors (GPCRs) use a complex series of intramolecular conformational changes to couple agonist binding to the binding and activation of cognate heterotrimeric G protein (Gαβγ). The mechanisms underlying this long-range activation have been identified using a variety of biochemic...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3549666/ https://ncbi.nlm.nih.gov/pubmed/22052489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-334-9_8 |
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