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Allosteric mechanisms of G protein coupled receptor signaling: a structural perspective

G protein-Coupled Receptors (GPCRs) use a complex series of intramolecular conformational changes to couple agonist binding to the binding and activation of cognate heterotrimeric G protein (Gαβγ). The mechanisms underlying this long-range activation have been identified using a variety of biochemic...

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Sonraí Bibleagrafaíochta
Main Authors: Thaker, Tarjani M., Kaya, Ali I., Preininger, Anita M., Hamm, Heidi E., Iverson, T.M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549666/
https://ncbi.nlm.nih.gov/pubmed/22052489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-334-9_8
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