Accumulation of Toxic α-Synuclein Oligomer within Endoplasmic Reticulum Occurs in α-Synucleinopathy In Vivo

In Parkinson's disease (PD) and other α-synucleinopathies, prefibrillar α-synuclein (αS) oligomer is implicated in the pathogenesis. However, toxic αS oligomers observed using in vitro systems are not generally seen to be associated with α-synucleinopathy in vivo. Thus, the pathologic significa...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Colla, Emanuela, Jensen, Poul H., Pletnikova, Olga, Troncoso, Juan C., Glabe, Charles, Lee, Michael K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2012
Aiheet:
Brief Communications
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548448/
https://ncbi.nlm.nih.gov/pubmed/22399752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5368-11.2012
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia