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Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
Homeostasis of self-renewing small intestinal crypts results from neutral competition between Lgr5 stem cells, small cycling cells located at crypt bottoms(1, 2). Lgr5 stem cells are interspersed between terminally differentiated Paneth cells, that are known to produce bactericidal products such as...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3547360/ https://ncbi.nlm.nih.gov/pubmed/21113151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09637 |
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