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Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes

Somatic cells have been proposed to be limited in the number of cell divisions they can undergo. This is thought to be a mechanism by which stem cells retain their integrity preventing disease. However, we have recently discovered intestinal crypt stem cells that persist for the lifetime of a mouse,...

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Bibliographic Details
Main Authors: Schepers, Arnout G, Vries, Robert, van den Born, Maaike, van de Wetering, Marc, Clevers, Hans
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061032/
https://ncbi.nlm.nih.gov/pubmed/21297579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.26
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