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Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes

Somatic cells have been proposed to be limited in the number of cell divisions they can undergo. This is thought to be a mechanism by which stem cells retain their integrity preventing disease. However, we have recently discovered intestinal crypt stem cells that persist for the lifetime of a mouse,...

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Detalhes bibliográficos
Main Authors: Schepers, Arnout G, Vries, Robert, van den Born, Maaike, van de Wetering, Marc, Clevers, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061032/
https://ncbi.nlm.nih.gov/pubmed/21297579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.26
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