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In vivo translation rates can substantially delay the cotranslational folding of the Escherichia coli cytosolic proteome
A question of fundamental importance concerning protein folding in vivo is whether the kinetics of translation or the thermodynamics of the ribosome nascent chain (RNC) complex is the major determinant of cotranslational folding behavior. This is because translation rates can reduce the probability...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3545769/ https://ncbi.nlm.nih.gov/pubmed/23256155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213624110 |
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