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Effects of protein size, thermodynamic stability, and net charge on cotranslational folding on the ribosome

During the last five decades, studies of protein folding in dilute buffer solutions have produced a rich picture of this complex process. In the cell, however, proteins can start to fold while still attached to the ribosome (cotranslational folding) and it is not yet clear how the ribosome affects t...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Farías-Rico, José Arcadio, Ruud Selin, Frida, Myronidi, Ioanna, Frühauf, Marie, von Heijne, Gunnar
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176590/
https://ncbi.nlm.nih.gov/pubmed/30224455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1812756115
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