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Effects of protein size, thermodynamic stability, and net charge on cotranslational folding on the ribosome

During the last five decades, studies of protein folding in dilute buffer solutions have produced a rich picture of this complex process. In the cell, however, proteins can start to fold while still attached to the ribosome (cotranslational folding) and it is not yet clear how the ribosome affects t...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Farías-Rico, José Arcadio, Ruud Selin, Frida, Myronidi, Ioanna, Frühauf, Marie, von Heijne, Gunnar
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176590/
https://ncbi.nlm.nih.gov/pubmed/30224455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1812756115
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